| Compound Information | SONAR Target prediction | | Name: | NOREPINEPHRINE | | Unique Identifier: | SPE01500436 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | | | Molecular Weight: | 159.098 g/mol | | X log p: | 5.47 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 0 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 4 | | Rotatable Bond Count: | 2 | | Canonical Smiles: | NCC(O)c1ccc(O)c(O)c1 | | Source: | synthetic | | Therapeutics: | adrenergic agonist, antihypotensive | | Generic_name: | NORADRENALINE | | Chemical_iupac_name: | L-NOREPINEPHRINE | | Drug_type: | Experimental | | Drugbank_id: | EXPT02050 | | Drug_category: | Phenylalanine Hydroxylase inhibitor | | Organisms_affected: | -1 |
| Species: |
4932 |
| Condition: |
FET3 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.5934±0.0402344 |
| Normalized OD Score: sc h |
0.8406±0.0443852 |
| Z-Score: |
-6.6582±1.59025 |
| p-Value: |
0.0000000156786 |
| Z-Factor: |
-0.250915 |
| Fitness Defect: |
17.971 |
| Bioactivity Statement: |
Active |
| Experimental Conditions | | | Library: | SPECMTS3 | | Plate Number and Position: | 19|A8 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 23.80 Celcius | | Date: | 2008-01-10 YYYY-MM-DD | | Plate CH Control (+): | 0.0406±0.00065 | | Plate DMSO Control (-): | 0.6779±0.01575 | | Plate Z-Factor: | 0.9237 |
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| 3810693 |
[2-(3,4-dihydroxyphenyl)-2-hydroxy-ethyl]azanium |
| 6398887 |
4-[(1R)-2-amino-1-hydroxy-ethyl]benzene-1,2-diol |
| 6914092 |
4-(2-amino-1,2,2-trideuterio-1-hydroxy-ethyl)benzene-1,2-diol |
| 6921839 |
[(2S)-2-(3,4-dihydroxyphenyl)-2-hydroxy-ethyl]azanium |
| 6921840 |
[(2R)-2-(3,4-dihydroxyphenyl)-2-hydroxy-ethyl]azanium |
| internal high similarity DBLink | Rows returned: 0 | |
| nonactive | Cluster 15753 | Additional Members: 7 | Rows returned: 6 | |
|
