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Compound InformationSONAR Target prediction
Name:

HYDROCORTISONE PHOSPHATE TRIETHYLAMINE

Unique Identifier:SPE01500340
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:457.173 g/mol
X log p:-2.384  (online calculus)
Lipinksi Failures0
TPSA116.37
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:4
Canonical Smiles:[Na+].[Na+].[O-]P([O-])(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3C(O)C
C21C
Source:semisynthetic
Therapeutics:glucocorticoid

Found: 205 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [205]
Species: 4932
Condition: BCK2
Replicates: 2
Raw OD Value: r im 0.7950±0.0370524
Normalized OD Score: sc h 1.0120±0.00889597
Z-Score: 0.5329±0.441077
p-Value: 0.611628
Z-Factor: -7.4464
Fitness Defect: 0.4916
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:12|E6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.90 Celcius
Date:2006-03-29 YYYY-MM-DD
Plate CH Control (+):0.038±0.00130
Plate DMSO Control (-):0.758±0.01725
Plate Z-Factor:0.9313
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DBLink | Rows returned: 8<< Back 1 2
5702070 disodium
(11S,17R)-11,17-dihydroxy-10,13-dimethyl-17-(2-phosphonatooxyacetyl)-2,6,7,8,9,11,12,14,15,16-decahydro-
1H-cyclopenta[a]phenanthren-3-one
6602442 [2-[(11S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]ph
enanthren-17-yl]-2-oxo-ethoxy]phosphonic acid

internal high similarity DBLink | Rows returned: 0

active | Cluster 10196 | Additional Members: 12 | Rows returned: 0

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