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Compound InformationSONAR Target prediction
Name:

FLUDROCORTISONE ACETATE

Unique Identifier:SPE01500299
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:391.241 g/mol
X log p:-0.363  (online calculus)
Lipinksi Failures0
TPSA60.44
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:4
Canonical Smiles:CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3(F)C(O)CC21C
Source:semisynthetic
Therapeutics:mineralocorticoid

Found: 205 nonactive as graph: single | with analogs [1] << Back 61 62 63 64 65 66 67 68 69 70  Next >> [205]
Species: 4932
Condition: MET16
Replicates: 2
Raw OD Value: r im 0.6627±0.00311127
Normalized OD Score: sc h 0.9986±0.00644718
Z-Score: -0.0725±0.326661
p-Value: 0.817798
Z-Factor: -64.2473
Fitness Defect: 0.2011
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:12|B4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.50 Celcius
Date:2007-10-18 YYYY-MM-DD
Plate CH Control (+):0.0402±0.00067
Plate DMSO Control (-):0.6517999999999999±0.01777
Plate Z-Factor:0.9133
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DBLink | Rows returned: 13<< Back 1 2 3
6957656 [2-[(8R,9R,10R,11R,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-d
ecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate

internal high similarity DBLink | Rows returned: 2
SPE01500231 0.9072
NRB 03816 0.9341

active | Cluster 13203 | Additional Members: 4 | Rows returned: 0
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