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Compound InformationSONAR Target prediction
Name:

FLUDROCORTISONE ACETATE

Unique Identifier:SPE01500299
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:391.241 g/mol
X log p:-0.363  (online calculus)
Lipinksi Failures0
TPSA60.44
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:6
Rotatable Bond Count:4
Canonical Smiles:CC(=O)OCC(=O)C1(O)CCC2C3CCC4=CC(=O)CCC4(C)C3(F)C(O)CC21C
Source:semisynthetic
Therapeutics:mineralocorticoid

Found: 205 nonactive as graph: single | with analogs [1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [205]
Species: 4932
Condition: BY4741-3rd
Replicates: 2
Raw OD Value: r im 0.6102±0.00282843
Normalized OD Score: sc h 0.9772±0.00270861
Z-Score: -0.2178±0.120061
p-Value: 0.828196
Z-Factor: -136.348
Fitness Defect: 0.1885
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:12|B4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.30 Celcius
Date:2007-09-25 YYYY-MM-DD
Plate CH Control (+):0.039425±0.00030
Plate DMSO Control (-):0.5975250000000001±0.02921
Plate Z-Factor:0.8464
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DBLink | Rows returned: 13<< Back 1 2 3
6957656 [2-[(8R,9R,10R,11R,13S,14S,17S)-9-fluoro-11,17-dihydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-d
ecahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate

internal high similarity DBLink | Rows returned: 2
SPE01500231 0.9072
NRB 03816 0.9341

active | Cluster 13203 | Additional Members: 4 | Rows returned: 0
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