Compound Information | SONAR Target prediction | Name: | DEXAMETHASONE SODIUM PHOSPHATE | Unique Identifier: | SPE01500232 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 489.19 g/mol | X log p: | 2.424 (online calculus) | Lipinksi Failures | 0 | TPSA | 116.37 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 8 | Rotatable Bond Count: | 4 | Canonical Smiles: | [Na+].[Na+].[O-]P([O-])(=O)OCC(=O)C1(O)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3( F)C(O)CC21C | Source: | semisynthetic | Therapeutics: | glucocorticoid, antiinflammatory |
Species: |
4932 |
Condition: |
ABP1 |
Replicates: |
2 |
Raw OD Value: r im |
0.6774±0.0053033 |
Normalized OD Score: sc h |
0.9745±0.00967211 |
Z-Score: |
-1.3177±0.550609 |
p-Value: |
0.220524 |
Z-Factor: |
-2.15179 |
Fitness Defect: |
1.5117 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | SPECMTS3 | Plate Number and Position: | 3|H5 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 22.00 Celcius | Date: | 2007-12-20 YYYY-MM-DD | Plate CH Control (+): | 0.0417±0.00053 | Plate DMSO Control (-): | 0.67005±0.01623 | Plate Z-Factor: | 0.9262 |
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5771591 |
[2-[(8R,9S,10R,11R,14S,16S)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octah ydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]phosphonic acid |
6431705 |
disodium (9R,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-17-(2-phosphonatooxyacetyl)-6,7,8,11,12,14,15,1 6-octahydrocyclopenta[a]phenanthren-3-one |
6431707 |
disodium 9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-17-(2-phosphonatooxyacetyl)-6,7,8,11,12,14,15,16-octahydrocy clopenta[a]phenanthren-3-one |
6560185 |
(8R,9R,10R,11R,13R,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-17-(2-phosphonatooxyacetyl)- 6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
6560186 |
[2-[(8R,9R,10R,11R,13R,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15, 16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]phosphonic acid |
6602441 |
[2-[(9R,10S,11S,13S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octa hydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethoxy]phosphonic acid |
internal high similarity DBLink | Rows returned: 0 | |
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