Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

DEMECLOCYCLINE HYDROCHLORIDE

Unique Identifier:SPE01500226
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:481.155 g/mol
X log p:3.68  (online calculus)
Lipinksi Failures0
TPSA54.45
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:10
Rotatable Bond Count:2
Canonical Smiles:Cl.CN(C)C1C2CC3C(O)c4c(Cl)ccc(O)c4C(=O)C3=C(O)C2(O)C(=O)C(C(N)=O)=C1O
Source:Streptomyces aureofaiens
Therapeutics:antibacterial
Generic_name:7-CHLOROTETRACYCLINE
Chemical_iupac_name:7-CHLOROTETRACYCLINE
Drug_type:Experimental
Drugbank_id:EXPT01049
Drug_category:Tetracycline Repressor inhibitor
Organisms_affected:-1

Found: 205 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [205]
Species: 4932
Condition: BY4741-3rd
Replicates: 2
Raw OD Value: r im 0.6165±0.0170413
Normalized OD Score: sc h 0.9668±0.00881314
Z-Score: -1.8253±0.448357
p-Value: 0.081823
Z-Factor: -16.8961
Fitness Defect: 2.5032
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:11|E7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.10 Celcius
Date:2007-09-25 YYYY-MM-DD
Plate CH Control (+):0.03945±0.00076
Plate DMSO Control (-):0.637325±0.16510
Plate Z-Factor:0.0729
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 5
SPE01500457 0.9146
SPE01500566 0.9298
LOPAC 00845 1.0000
SPE01500186 1.0000
SPE01500829 1.0000

nonactive | Cluster 12393 | Additional Members: 20 | Rows returned: 161 2 3 Next >> 
LOPAC 00607 0.554347826086957
LAT004C03 0.554347826086957
SPE01505684 0.452631578947368
SPE01500414 0.448275862068966
Prest626 0.448275862068966
Prest235 0.353658536585366

Service provided by the Mike Tyers Laboratory