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Compound InformationSONAR Target prediction
Name:

AMILORIDE HYDROCHLORIDE

Unique Identifier:SPE01500112
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:257.016 g/mol
X log p:-2.813  (online calculus)
Lipinksi Failures0
TPSA41.79
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:3
Canonical Smiles:Cl.NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Source:synthetic
Reference:Biochim Biophys Acta 944: 383 (1988)
Therapeutics:Na+ channel inhibitor, diuretic

Found: 616 nonactive | as graph: single | with analogs [1] << Back 581 582 583 584 585 586 587 588 589 590  Next >> [616]
Species: 4932
Condition: SMI1
Replicates: 2
Raw OD Value: r im 0.5802±0.0210011
Normalized OD Score: sc h 0.9301±0.0224468
Z-Score: -1.4538±0.348165
p-Value: 0.158168
Z-Factor: -1.23673
Fitness Defect: 1.8441
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:10|D9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.60 Celcius
Date:2005-12-20 YYYY-MM-DD
Plate CH Control (+):0.03875000000000001±0.00246
Plate DMSO Control (-):0.6314±0.01665
Plate Z-Factor:0.9302
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
SPE01503999 0.9016
LOPAC 00165 1.0000

active | Cluster 4060 | Additional Members: 8 | Rows returned: 1
SPE01504215 0.462962962962963

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