Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

AMILORIDE HYDROCHLORIDE

Unique Identifier:SPE01500112
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:257.016 g/mol
X log p:-2.813  (online calculus)
Lipinksi Failures0
TPSA41.79
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:3
Canonical Smiles:Cl.NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Source:synthetic
Reference:Biochim Biophys Acta 944: 383 (1988)
Therapeutics:Na+ channel inhibitor, diuretic

Found: 616 nonactive | as graph: single | with analogs [1] << Back 521 522 523 524 525 526 527 528 529 530  Next >> [616]
Species: 4932
Condition: CNB1
Replicates: 2
Raw OD Value: r im 0.8188±0.0105359
Normalized OD Score: sc h 0.9937±0.0088929
Z-Score: -0.3128±0.444188
p-Value: 0.76485
Z-Factor: -12.6885
Fitness Defect: 0.2681
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:10|D9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.60 Celcius
Date:2006-03-03 YYYY-MM-DD
Plate CH Control (+):0.0392±0.00148
Plate DMSO Control (-):0.813375±0.01085
Plate Z-Factor:0.9604
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
SPE01503999 0.9016
LOPAC 00165 1.0000

active | Cluster 4060 | Additional Members: 8 | Rows returned: 1
SPE01504215 0.462962962962963

Service provided by the Mike Tyers Laboratory