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Compound InformationSONAR Target prediction
Name:

AMILORIDE HYDROCHLORIDE

Unique Identifier:SPE01500112
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:257.016 g/mol
X log p:-2.813  (online calculus)
Lipinksi Failures0
TPSA41.79
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:3
Canonical Smiles:Cl.NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Source:synthetic
Reference:Biochim Biophys Acta 944: 383 (1988)
Therapeutics:Na+ channel inhibitor, diuretic

Found: 616 nonactive | as graph: single | with analogs [1] << Back 411 412 413 414 415 416 417 418 419 420  Next >> [616]
Species: 4932
Condition: ABP1
Replicates: 2
Raw OD Value: r im 0.7141±0.0248194
Normalized OD Score: sc h 1.0259±0.0365302
Z-Score: 1.3620±1.93072
p-Value: 0.501906
Z-Factor: -6.77472
Fitness Defect: 0.6893
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:4|C8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:22.10 Celcius
Date:2007-12-20 YYYY-MM-DD
Plate CH Control (+):0.042050000000000004±0.00148
Plate DMSO Control (-):0.673525±0.01681
Plate Z-Factor:0.9154
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
SPE01503999 0.9016
LOPAC 00165 1.0000

active | Cluster 4060 | Additional Members: 8 | Rows returned: 1
SPE01504215 0.462962962962963

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