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Compound InformationSONAR Target prediction
Name:

AMILORIDE HYDROCHLORIDE

Unique Identifier:SPE01500112
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:257.016 g/mol
X log p:-2.813  (online calculus)
Lipinksi Failures0
TPSA41.79
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:3
Canonical Smiles:Cl.NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Source:synthetic
Reference:Biochim Biophys Acta 944: 383 (1988)
Therapeutics:Na+ channel inhibitor, diuretic

Found: 616 nonactive | as graph: single | with analogs [1] << Back 281 282 283 284 285 286 287 288 289 290  Next >> [616]
Species: 4932
Condition: SPE01504082
Replicates: 2
Raw OD Value: r im 0.1188±0.00289914
Normalized OD Score: sc h 1.0935±0.143664
Z-Score: 0.0489±0.117453
p-Value: 0.93389
Z-Factor: -3.42224
Fitness Defect: 0.0684
Bioactivity Statement: Nonactive
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:1|G5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:21.40 Celcius
Date:2007-03-22 YYYY-MM-DD
Plate CH Control (+):0.042124999999999996±0.00144
Plate DMSO Control (-):0.13892500000000002±0.29478
Plate Z-Factor:-1.7621
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
SPE01503999 0.9016
LOPAC 00165 1.0000

active | Cluster 4060 | Additional Members: 8 | Rows returned: 1
SPE01504215 0.462962962962963

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