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Compound InformationSONAR Target prediction
Name:

AMILORIDE HYDROCHLORIDE

Unique Identifier:SPE01500112
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:257.016 g/mol
X log p:-2.813  (online calculus)
Lipinksi Failures0
TPSA41.79
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:3
Canonical Smiles:Cl.NC(=N)NC(=O)c1nc(Cl)c(N)nc1N
Source:synthetic
Reference:Biochim Biophys Acta 944: 383 (1988)
Therapeutics:Na+ channel inhibitor, diuretic

Found: 2 active | as graph: single | with analogs 1 2 Next >> 
Species: 4932
Condition: YPT6
Replicates: 2
Raw OD Value: r im 0.5407±0.0120915
Normalized OD Score: sc h 1.4088±0.0512321
Z-Score: 4.1383±0.0575111
p-Value: 0.0000355106
Z-Factor: 0.28067
Fitness Defect: 10.2457
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:4|C8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.40 Celcius
Date:2008-06-05 YYYY-MM-DD
Plate CH Control (+):0.0411±0.00068
Plate DMSO Control (-):0.50915±0.02329
Plate Z-Factor:0.8365
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 2
SPE01503999 0.9016
LOPAC 00165 1.0000

nonactive | Cluster 4060 | Additional Members: 8 | Rows returned: 7<< Back 1 2
LOPAC 00165 0

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