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Compound InformationSONAR Target prediction
Name:

DACTINOMYCIN

Unique Identifier:SPE00330001
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:1164.74 g/mol
X log p:0.0749999999999996  (online calculus)
Lipinksi Failures1
TPSA274.92
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:26
Rotatable Bond Count:10
Canonical Smiles:CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3Oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C
(C)C)N(C)C(=O)CN(C)C(=O)C6CCCC6C(=O)C(NC5=O)C(C)C)c4=Nc32)C(C)OC(=O)C(
C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCC2C1=O
Class:macrolide
Source:Actinomyces spp
Therapeutics:antineoplastic, intercalating agent

Found: 66 active | as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [66]
Species: 4932
Condition: SPE00100009
Replicates: 2
Raw OD Value: r im 0.4367±0.0465983
Normalized OD Score: sc h 9.4695±0.951862
Z-Score: 105.9280±23.4685
p-Value: 0
Z-Factor: -2.34947
Fitness Defect: INF
Bioactivity Statement: Active
Experimental Conditions
Library:SpectrumTMP
Plate Number and Position:1|G3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:22.30 Celcius
Date:2006-11-29 YYYY-MM-DD
Plate CH Control (+):0.041025±0.00186
Plate DMSO Control (-):0.054075±0.24731
Plate Z-Factor:-2.6608
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DBLink | Rows returned: 1
2019 2-amino-4,6-dimethyl-3-oxo-N,N--bis(7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-dipropan-2-yl-8-oxa-1,4,
11,14-tetrazabicyclo[14.3.0]nonadec-6-yl)phenoxazine-1,9-dicarboxamide

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 1492 | Additional Members: 3 | Rows returned: 1
LAT002G11 0

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