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Compound InformationSONAR Target prediction
Name:

DACTINOMYCIN

Unique Identifier:SPE00330001
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:1164.74 g/mol
X log p:0.0749999999999996  (online calculus)
Lipinksi Failures1
TPSA274.92
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:26
Rotatable Bond Count:10
Canonical Smiles:CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3Oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C
(C)C)N(C)C(=O)CN(C)C(=O)C6CCCC6C(=O)C(NC5=O)C(C)C)c4=Nc32)C(C)OC(=O)C(
C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCC2C1=O
Class:macrolide
Source:Actinomyces spp
Therapeutics:antineoplastic, intercalating agent

Found: 554 nonactive | as graph: single | with analogs [1] << Back 531 532 533 534 535 536 537 538 539 540  Next >> [554]
Species: 4932
Condition: PRE9
Replicates: 2
Raw OD Value: r im 0.5858±0.0100409
Normalized OD Score: sc h 0.9418±0.000177863
Z-Score: -2.2125±0.0211091
p-Value: 0.026946
Z-Factor: -12.1609
Fitness Defect: 3.6139
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:22|A4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.40 Celcius
Date:2007-10-04 YYYY-MM-DD
Plate CH Control (+):0.04055±0.00121
Plate DMSO Control (-):0.617575±0.20278
Plate Z-Factor:-0.2308
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DBLink | Rows returned: 1
2019 2-amino-4,6-dimethyl-3-oxo-N,N--bis(7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-dipropan-2-yl-8-oxa-1,4,
11,14-tetrazabicyclo[14.3.0]nonadec-6-yl)phenoxazine-1,9-dicarboxamide

internal high similarity DBLink | Rows returned: 0

active | Cluster 1492 | Additional Members: 3 | Rows returned: 1
LAT002G11 0

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