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Compound InformationSONAR Target prediction
Name:

DACTINOMYCIN

Unique Identifier:SPE00330001
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:1164.74 g/mol
X log p:0.0749999999999996  (online calculus)
Lipinksi Failures1
TPSA274.92
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:26
Rotatable Bond Count:10
Canonical Smiles:CC(C)C1NC(=O)C(NC(=O)c2ccc(C)c3Oc4c(C)c(=O)c(N)c(C(=O)NC5C(C)OC(=O)C(C
(C)C)N(C)C(=O)CN(C)C(=O)C6CCCC6C(=O)C(NC5=O)C(C)C)c4=Nc32)C(C)OC(=O)C(
C(C)C)N(C)C(=O)CN(C)C(=O)C2CCCC2C1=O
Class:macrolide
Source:Actinomyces spp
Therapeutics:antineoplastic, intercalating agent

Found: 554 nonactive | as graph: single | with analogs [1] << Back 521 522 523 524 525 526 527 528 529 530  Next >> [554]
Species: 4932
Condition: MT2481-pdr1pdr3
Replicates: 2
Raw OD Value: r im 0.6622±0.00120208
Normalized OD Score: sc h 0.9376±0.00330092
Z-Score: -1.9795±0.0587801
p-Value: 0.0479568
Z-Factor: -0.345386
Fitness Defect: 3.0375
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:22|A4
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.10 Celcius
Date:2006-05-02 YYYY-MM-DD
Plate CH Control (+):0.038025±0.00103
Plate DMSO Control (-):0.686375±0.01587
Plate Z-Factor:0.9145
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DBLink | Rows returned: 1
2019 2-amino-4,6-dimethyl-3-oxo-N,N--bis(7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-dipropan-2-yl-8-oxa-1,4,
11,14-tetrazabicyclo[14.3.0]nonadec-6-yl)phenoxazine-1,9-dicarboxamide

internal high similarity DBLink | Rows returned: 0

active | Cluster 1492 | Additional Members: 3 | Rows returned: 1
LAT002G11 0

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