Compound Information | SONAR Target prediction | Name: | DESOXYCORTICOSTERONE ACETATE | Unique Identifier: | SPE00300029 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 340.244 g/mol | X log p: | 1.899 (online calculus) | Lipinksi Failures | 0 | TPSA | 60.44 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 4 | Rotatable Bond Count: | 4 | Canonical Smiles: | CC(=O)OCC(=O)C1CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C | Source: | adrenocortex | Therapeutics: | mineralocorticoid |
Species: |
4932 |
Condition: |
VPH1 |
Replicates: |
2 |
Raw OD Value: r im |
0.2749±0.00381838 |
Normalized OD Score: sc h |
0.7343±0.0135687 |
Z-Score: |
-4.7901±0.041546 |
p-Value: |
0.00000168382 |
Z-Factor: |
0.31809 |
Fitness Defect: |
13.2944 |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | SPECMTS3 | Plate Number and Position: | 7|F8 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 24.40 Celcius | Date: | 2008-03-01 YYYY-MM-DD | Plate CH Control (+): | 0.040225±0.00043 | Plate DMSO Control (-): | 0.3597±0.01683 | Plate Z-Factor: | 0.7870 |
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11875276 |
[(8R,9R,10R,13S,14R,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta [a]phenanthren-17-yl] acetate |
11875277 |
[(8R,9S,10R,13S,14R,17R)-17-acetyl-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta [a]phenanthren-17-yl] acetate |
internal high similarity DBLink | Rows returned: 2 | |
active | Cluster 2094 | Additional Members: 20 | Rows returned: 6 | |
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