Compound Information | SONAR Target prediction | Name: | CHOLESTAN-3-ONE | Unique Identifier: | SPE00270088 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | C27H46O | Molecular Weight: | 341.296 g/mol | X log p: | 1.754 (online calculus) | Lipinksi Failures | 0 | TPSA | 17.07 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 1 | Rotatable Bond Count: | 5 | Canonical Smiles: | CC(C)CCCC(C)C1CCC2C3CCC4CC(=O)CCC4(C)C3CCC12C | Source: | ex minor mammalian sterol | Generic_name: | 5ALPHA-ANDROSTAN-3,17-DIONE | Chemical_iupac_name: | 5ALPHA-ANDROSTAN-3,17-DIONE | Drug_type: | Experimental | Drugbank_id: | EXPT00262 | Drug_category: | Estradiol 17 Beta-Dehydrogenase 1 inhibitor | Organisms_affected: | -1 |
Species: |
4932 |
Condition: |
ARF1 |
Replicates: |
2 |
Raw OD Value: r im |
0.6887±0.0272236 |
Normalized OD Score: sc h |
1.0482±0.0206568 |
Z-Score: |
2.3365±1.0084 |
p-Value: |
0.053388 |
Z-Factor: |
-2.61058 |
Fitness Defect: |
2.9302 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | Spectrum | Plate Number and Position: | 6|D8 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 24.20 Celcius | Date: | 2007-10-02 YYYY-MM-DD | Plate CH Control (+): | 0.041374999999999995±0.00060 | Plate DMSO Control (-): | 0.66265±0.03344 | Plate Z-Factor: | 0.8393 |
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443 |
10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione |
454 |
octanal |
984 |
hexadecanal |
2537 |
1,7,7-trimethylnorbornan-2-one |
6986 |
5-methyl-2-propan-2-yl-cyclohexan-1-one |
7016 |
2-cyclohexylcyclohexan-1-one |
internal high similarity DBLink | Rows returned: 17 | 1 2 3 Next >> |
nonactive | Cluster 5819 | Additional Members: 6 | Rows returned: 1 | |
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