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Compound InformationSONAR Target prediction
Name:

5,7-DIHYDROXYISOFLAVONE

Unique Identifier:SPE00240565
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:244.158 g/mol
X log p:16.755  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:1
Canonical Smiles:Oc1cc(O)c2C(=O)C(=COc2c1)c1ccccc1
Class:isoflavone
Source:Arachis hypogaea & Derris spp
Reference:J Chem Soc 1953:1852; CA 104:165440 (1986)

Found: 85 active | as graph: single | with analogs [1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [85]
Species: 4932
Condition: IRE1
Replicates: 2
Raw OD Value: r im 0.5280±0.0497803
Normalized OD Score: sc h 0.7394±0.0712937
Z-Score: -14.0781±4.26828
p-Value: 9.80358e-29
Z-Factor: -2.67111
Fitness Defect: 64.4922
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:4|G8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.80 Celcius
Date:2007-11-23 YYYY-MM-DD
Plate CH Control (+):0.0401±0.00070
Plate DMSO Control (-):0.7075750000000001±0.13088
Plate Z-Factor:0.3396
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DBLink | Rows returned: 1
5377381 5,7-dihydroxy-3-phenyl-chromen-4-one

internal high similarity DBLink | Rows returned: 17<< Back 1 2 3
SPE10100004 0.9752
RJC 00206 0.9831
SPE10100003 0.9833
LOPAC 00433 0.9916
SPE00210296 0.9916

active | Cluster 14679 | Additional Members: 9 | Rows returned: 4
SPE01500726 0.362068965517241
SPE00210296 0.269230769230769
SPE10100004 0.245283018867924
SPE10100003 0

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