Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

DIHYDROLANOSTEROL

Unique Identifier:SPE00240449
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C30H52O
Molecular Weight:376.32 g/mol
X log p:0.339  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:5
Canonical Smiles:CC(C)CCCC(C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Source:ex wool fat of sheep
Reference:J Chem Soc 1951: 3147
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 101 nonactive as graph: single | with analogs [1] << Back 61 62 63 64 65 66 67 68 69 70  Next >> [101]
Species: 4932
Condition: POL32
Replicates: 2
Raw OD Value: r im 0.5979±0.0524673
Normalized OD Score: sc h 0.9875±0.0176392
Z-Score: -0.3498±0.492039
p-Value: 0.741896
Z-Factor: -39.5475
Fitness Defect: 0.2985
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|G7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.20 Celcius
Date:2006-02-16 YYYY-MM-DD
Plate CH Control (+):0.039525000000000005±0.00081
Plate DMSO Control (-):0.5742499999999999±0.05578
Plate Z-Factor:0.6092
png
ps
pdf

DBLink | Rows returned: 277[1] << Back 41 42 43 44 45 46 47
16061334 (3S,5S,10S,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodeca
hydro-1H-cyclopenta[a]phenanthren-3-ol

internal high similarity DBLink | Rows returned: 111 2 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 3
SPE00100583 0.253012048192771
SPE00201697 0
SPE00240470 0

Service provided by the Mike Tyers Laboratory