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Compound InformationSONAR Target prediction
Name:

DIHYDROLANOSTEROL

Unique Identifier:SPE00240449
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C30H52O
Molecular Weight:376.32 g/mol
X log p:0.339  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:5
Canonical Smiles:CC(C)CCCC(C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Source:ex wool fat of sheep
Reference:J Chem Soc 1951: 3147
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 101 nonactive as graph: single | with analogs [1] << Back 51 52 53 54 55 56 57 58 59 60  Next >> [101]
Species: 4932
Condition: MDH1
Replicates: 2
Raw OD Value: r im 0.7836±0.0135764
Normalized OD Score: sc h 0.9877±0.0130803
Z-Score: -0.6630±0.669859
p-Value: 0.552774
Z-Factor: -37.1306
Fitness Defect: 0.5928
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|G7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.30 Celcius
Date:2007-08-07 YYYY-MM-DD
Plate CH Control (+):0.0408±0.00066
Plate DMSO Control (-):0.779925±0.14217
Plate Z-Factor:0.4083
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DBLink | Rows returned: 277[1] << Back 41 42 43 44 45 46 47
16061334 (3S,5S,10S,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodeca
hydro-1H-cyclopenta[a]phenanthren-3-ol

internal high similarity DBLink | Rows returned: 111 2 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 3
SPE00100583 0.253012048192771
SPE00201697 0
SPE00240470 0

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