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Compound InformationSONAR Target prediction
Name:

DIHYDROLANOSTEROL

Unique Identifier:SPE00240449
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C30H52O
Molecular Weight:376.32 g/mol
X log p:0.339  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:5
Canonical Smiles:CC(C)CCCC(C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Source:ex wool fat of sheep
Reference:J Chem Soc 1951: 3147
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 101 nonactive as graph: single | with analogs [1] << Back 91 92 93 94 95 96 97 98 99 100  Next >> [101]
Species: 4932
Condition: TOP1
Replicates: 2
Raw OD Value: r im 0.6057±0.000282843
Normalized OD Score: sc h 1.0165±0.0131149
Z-Score: 0.2717±0.224783
p-Value: 0.788462
Z-Factor: -6.62308
Fitness Defect: 0.2377
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|G7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.80 Celcius
Date:2006-04-26 YYYY-MM-DD
Plate CH Control (+):0.039075±0.00240
Plate DMSO Control (-):0.58405±0.02038
Plate Z-Factor:0.8873
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DBLink | Rows returned: 277[1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [47]
5316231 2-[(4R)-4,8-dimethyl-1-spiro[4.5]dec-8-enyl]propan-2-ol
5316466 (10R,13S)-17-(5-ethyl-6-methyl-heptan-2-yl)-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H-
cyclopenta[a]phenanthren-3-ol
5316709 (3S,10R,13S,17R)-17-[(E)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodeca
hydro-1H-cyclopenta[a]phenanthren-3-ol
5316742 2-[(5R)-6,10-dimethyl-2-spiro[4.5]dec-9-enyl]propan-2-ol
5316882 (3S,10S,13S)-10,13-dimethyl-17-(5,5,6-trimethylheptan-2-yl)-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1H
-cyclopenta[a]phenanthren-3-ol
5316992 (3S,10S,13R,17R)-17-(1-hydroxy-6-methyl-5-methylidene-heptan-2-yl)-4,4,10,13,14-pentamethyl-2,3,5,6,7,11
,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol

internal high similarity DBLink | Rows returned: 112 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 3
SPE00100583 0.253012048192771
SPE00201697 0
SPE00240470 0

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