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Compound InformationSONAR Target prediction
Name:

DIHYDROLANOSTEROL

Unique Identifier:SPE00240449
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C30H52O
Molecular Weight:376.32 g/mol
X log p:0.339  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:5
Canonical Smiles:CC(C)CCCC(C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Source:ex wool fat of sheep
Reference:J Chem Soc 1951: 3147
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 101 nonactive as graph: single | with analogs [1] << Back 81 82 83 84 85 86 87 88 89 90  Next >> [101]
Species: 4932
Condition: SER1
Replicates: 2
Raw OD Value: r im 0.5395±0.0413657
Normalized OD Score: sc h 0.9319±0.0257943
Z-Score: -2.1333±0.753965
p-Value: 0.0586086
Z-Factor: -16.0723
Fitness Defect: 2.8369
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|G7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:28.10 Celcius
Date:2007-09-17 YYYY-MM-DD
Plate CH Control (+):0.039525000000000005±0.00046
Plate DMSO Control (-):0.5672250000000001±0.10392
Plate Z-Factor:0.3813
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DBLink | Rows returned: 277[1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [47]
556577 2,3,3a,4,7,7a-hexahydro-1H-inden-2-ol
565337 17-(5-ethyl-6-methyl-heptan-2-yl)-10,13-dimethyl-2,3,4,5,6,7,8,12,14,15,16,17-dodecahydro-1H-cyclopenta[
a]phenanthren-3-ol
577203 n/a
578322 n/a
584538 2,2,10,13-tetramethyl-17-(6-methylheptan-2-yl)-1,3,4,5,6,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phe
nanthren-3-ol
585856 1,1,4a,7,7-pentamethyl-3,4,4b,5,6,8,10,10a-octahydro-2H-phenanthren-2-ol

internal high similarity DBLink | Rows returned: 112 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 3
SPE00100583 0.253012048192771
SPE00201697 0
SPE00240470 0

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