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Compound InformationSONAR Target prediction
Name:

DIHYDROLANOSTEROL

Unique Identifier:SPE00240449
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C30H52O
Molecular Weight:376.32 g/mol
X log p:0.339  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:5
Canonical Smiles:CC(C)CCCC(C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Source:ex wool fat of sheep
Reference:J Chem Soc 1951: 3147
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 101 nonactive as graph: single | with analogs [1] << Back 81 82 83 84 85 86 87 88 89 90  Next >> [101]
Species: 4932
Condition: SPO22
Replicates: 2
Raw OD Value: r im 0.3355±0.000353553
Normalized OD Score: sc h 0.9176±0.00849117
Z-Score: -1.0112±0.118159
p-Value: 0.313596
Z-Factor: -2.56404
Fitness Defect: 1.1596
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Spectrum
Plate Number and Position:24|G7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2006-05-12 YYYY-MM-DD
Plate CH Control (+):0.039225±0.00053
Plate DMSO Control (-):0.34562499999999996±0.02446
Plate Z-Factor:0.7888
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DBLink | Rows returned: 277[1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [47]
390622 (3S,4S,10S,13R,14R,17R)-4,10,13,14-tetramethyl-17-[(2R)-6-methyl-5-methylidene-heptan-2-yl]-1,2,3,4,5,6,
7,11,12,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ol
428925 n/a
440371 (3S,5S,10S,13S,14R,17R)-10,13-dimethyl-17-[(2R)-6-methyl-5-methylidene-heptan-2-yl]-2,3,4,5,6,7,11,12,14
,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
440375 (3S,5S,10S,13S,14R,17R)-4,4,10,13-tetramethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,3,5,6,9,11,12,14,15,16,1
7-dodecahydrocyclopenta[a]phenanthren-3-ol
440556 (4S,5S)-4,10,13-trimethyl-17-(6-methylhept-5-en-2-yl)-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1H-cyclo
penta[a]phenanthren-3-ol
440557 (3S,9R,10R,13S,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-do
decahydro-1H-cyclopenta[a]phenanthren-3-ol

internal high similarity DBLink | Rows returned: 112 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 3
SPE00100583 0.253012048192771
SPE00201697 0
SPE00240470 0

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