Compound Information | SONAR Target prediction | Name: | DANTHRON | Unique Identifier: | SPE00211468 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 232.147 g/mol | X log p: | 11.828 (online calculus) | Lipinksi Failures | 1 | TPSA | 34.14 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 4 | Rotatable Bond Count: | 0 | Canonical Smiles: | Oc1cccc2c(=O)c3cccc(O)c3c(=O)c12 | Class: | quinone | Source: | Rheum palmatum, Xyris semifuscata | Reference: | JACS 53: 4112 (1931) | Therapeutics: | cathartic |
Species: |
4932 |
Condition: |
CNB1 |
Replicates: |
2 |
Raw OD Value: r im |
0.5754±0.0374767 |
Normalized OD Score: sc h |
0.6969±0.0491297 |
Z-Score: |
-14.9745±2.22003 |
p-Value: |
2.83679e-41 |
Z-Factor: |
0.335725 |
Fitness Defect: |
93.3633 |
Bioactivity Statement: |
Active |
Experimental Conditions | | Library: | Spectrum | Plate Number and Position: | 6|A3 | Drug Concentration: | 50.00 nM | OD Absorbance: | 600 nm | Robot Temperature: | 25.10 Celcius | Date: | 2006-03-03 YYYY-MM-DD | Plate CH Control (+): | 0.0386±0.00112 | Plate DMSO Control (-): | 0.8044250000000001±0.01496 | Plate Z-Factor: | 0.9408 |
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DBLink | Rows returned: 1 | |
2950 |
1,8-dihydroxyanthracene-9,10-dione |
internal high similarity DBLink | Rows returned: 0 | |
active | Cluster 7565 | Additional Members: 10 | Rows returned: 5 | |
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