Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

4,6-DIMETHOXY-5-METHYLISOFLAVONE

Unique Identifier:SPE00211076
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:280.19 g/mol
X log p:15.438  (online calculus)
Lipinksi Failures1
TPSA44.76
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:3
Canonical Smiles:COc1cc2OC=C(C(=O)c2c(OC)c1C)c1ccccc1
Source:analog

Found: 23 active | as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [23]
Species: 4932
Condition: IRE1
Replicates: 2
Raw OD Value: r im 0.6373±0.00254558
Normalized OD Score: sc h 0.9115±0.00343377
Z-Score: -4.7643±0.331902
p-Value: 0.00000324266
Z-Factor: -158.672
Fitness Defect: 12.6391
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:22|G6
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.00 Celcius
Date:2007-11-23 YYYY-MM-DD
Plate CH Control (+):0.040025±0.00048
Plate DMSO Control (-):0.6973±0.17527
Plate Z-Factor:0.1034
png
ps
pdf

DBLink | Rows returned: 1
6710721 5,7-dimethoxy-6-methyl-3-phenyl-chromen-4-one

internal high similarity DBLink | Rows returned: 9<< Back 1 2
SPE01500726 0.9160
SPE10100004 0.9160
SPE00201355 0.9474

active | Cluster 9315 | Additional Members: 4 | Rows returned: 1
SPE00200763 0

Service provided by the Mike Tyers Laboratory