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Compound InformationSONAR Target prediction
Name:

EUPHOL

Unique Identifier:SPE00201697
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:376.32 g/mol
X log p:2.412  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:4
Canonical Smiles:CC(CCC=C(C)C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Class:triterpene
Source:Euphorbia spp.
Reference:J Chem Soc 1944:249; 1958:179
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 52 active | as graph: single | with analogs [1] << Back 41 42 43 44 45 46 47 48 49 50  Next >> [52]
Species: 4932
Condition: SSE1
Replicates: 2
Raw OD Value: r im 0.6115±0.0178898
Normalized OD Score: sc h 1.2647±0.0137982
Z-Score: 7.1026±0.0510406
p-Value: 0.00000000000126544
Z-Factor: 0.288518
Fitness Defect: 27.3956
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:25|A8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.10 Celcius
Date:2008-05-01 YYYY-MM-DD
Plate CH Control (+):0.04135±0.00062
Plate DMSO Control (-):0.444925±0.02161
Plate Z-Factor:0.8263
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DBLink | Rows returned: 277[1] << Back 41 42 43 44 45 46 47
16061334 (3S,5S,10S,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodeca
hydro-1H-cyclopenta[a]phenanthren-3-ol

internal high similarity DBLink | Rows returned: 111 2 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 2
SPE00100583 0.253012048192771
SPE00240470 0

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