Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

EUPHOL

Unique Identifier:SPE00201697
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:376.32 g/mol
X log p:2.412  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:4
Canonical Smiles:CC(CCC=C(C)C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Class:triterpene
Source:Euphorbia spp.
Reference:J Chem Soc 1944:249; 1958:179
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 52 active | as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [52]
Species: 4932
Condition: GAS1
Replicates: 2
Raw OD Value: r im 0.4074±0.0912168
Normalized OD Score: sc h 1.4196±0.014701
Z-Score: 4.1932±0.582968
p-Value: 0.0000801626
Z-Factor: 0.399697
Fitness Defect: 9.4315
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:4|B2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:23.20 Celcius
Date:2006-01-20 YYYY-MM-DD
Plate CH Control (+):0.046475±0.00225
Plate DMSO Control (-):0.47387499999999994±0.03283
Plate Z-Factor:0.6131
png
ps
pdf

DBLink | Rows returned: 277[1] << Back 41 42 43 44 45 46 47
16061334 (3S,5S,10S,13R,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodeca
hydro-1H-cyclopenta[a]phenanthren-3-ol

internal high similarity DBLink | Rows returned: 111 2 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 2
SPE00100583 0.253012048192771
SPE00240470 0

Service provided by the Mike Tyers Laboratory