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Compound InformationSONAR Target prediction
Name:

EUPHOL

Unique Identifier:SPE00201697
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:376.32 g/mol
X log p:2.412  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:4
Canonical Smiles:CC(CCC=C(C)C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Class:triterpene
Source:Euphorbia spp.
Reference:J Chem Soc 1944:249; 1958:179
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 52 active | as graph: single | with analogs [1] << Back 41 42 43 44 45 46 47 48 49 50  Next >> [52]
Species: 4932
Condition: SRL3
Replicates: 2
Raw OD Value: r im 0.7835±0.0312541
Normalized OD Score: sc h 1.1045±0.0362543
Z-Score: 5.9589±2.06311
p-Value: 0.00000339628
Z-Factor: -0.64414
Fitness Defect: 12.5928
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:25|A8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.00 Celcius
Date:2008-09-17 YYYY-MM-DD
Plate CH Control (+):0.04227500000000001±0.00122
Plate DMSO Control (-):0.69465±0.01775
Plate Z-Factor:0.9170
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DBLink | Rows returned: 277[1] << Back 41 42 43 44 45 46 47 Next >> [47]
7092803 (3R,5S,9R,10R,13S,14S,17R)-17-[(E,2S,5R)-5-ethyl-6-methyl-hept-3-en-2-yl]-10,13-dimethyl-2,3,4,5,6,9,11,
12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
7093007 (3S,4aR,6aS,6bS,8aR,12aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,13,14-tetr
adecahydropicen-3-ol
7093008 (3S,4aS,6aS,6bS,8aR,12aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,13,14-tetr
adecahydropicen-3-ol
7093734 (3S,4aR,6aS,6bS,8aR,12aR,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,13,14-tetr
adecahydropicen-3-ol
7093735 (3R,4aR,6aS,6bS,8aR,12aS,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,13,14-tetr
adecahydropicen-3-ol
7093736 (3R,4aR,6aS,6bS,8aR,12aR,14bS)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,13,14-tetr
adecahydropicen-3-ol

internal high similarity DBLink | Rows returned: 112 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 2
SPE00100583 0.253012048192771
SPE00240470 0

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