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Compound InformationSONAR Target prediction
Name:

EUPHOL

Unique Identifier:SPE00201697
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:376.32 g/mol
X log p:2.412  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:4
Canonical Smiles:CC(CCC=C(C)C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Class:triterpene
Source:Euphorbia spp.
Reference:J Chem Soc 1944:249; 1958:179
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 52 active | as graph: single | with analogs [1] << Back 51 52 Next >> [52]
Species: 4932
Condition: SWC5
Replicates: 2
Raw OD Value: r im 0.7377±0.00120208
Normalized OD Score: sc h 1.0894±0.00316446
Z-Score: 4.0437±0.180024
p-Value: 0.0000601034
Z-Factor: 0.0991629
Fitness Defect: 9.7194
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:25|A8
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.10 Celcius
Date:2008-06-19 YYYY-MM-DD
Plate CH Control (+):0.039675±0.00041
Plate DMSO Control (-):0.6616±0.01561
Plate Z-Factor:0.9318
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DBLink | Rows returned: 277[1] << Back 31 32 33 34 35 36 37 38 39 40  Next >> [47]
6428413 2-[(4S)-4,8-dimethyl-1-spiro[4.5]dec-8-enyl]propan-2-ol
6428428 2-[(2S,4aS)-4a,8-dimethyl-2,3,4,5,6,8a-hexahydro-1H-naphthalen-2-yl]propan-2-ol
6428647 (3S,5S)-17-(5-ethyl-6-methyl-hept-5-en-2-yl)-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H
-cyclopenta[a]phenanthren-3-ol
6428648 (3S,5S)-10,13-dimethyl-17-[(E)-5-propan-2-ylhept-5-en-2-yl]-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1H
-cyclopenta[a]phenanthren-3-ol
6428652 (3S,5S)-17-(5-ethyl-6-methyl-heptan-2-yl)-10,13-dimethyl-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1H-cy
clopenta[a]phenanthren-3-ol
6428661 (3S,5S)-17-(5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,5,6,7,11,12,14,15,16,17-dodecahydro-1H-cyclope
nta[a]phenanthren-3-ol

internal high similarity DBLink | Rows returned: 112 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 2
SPE00100583 0.253012048192771
SPE00240470 0

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