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Compound InformationSONAR Target prediction
Name:

EUPHOL

Unique Identifier:SPE00201697
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:376.32 g/mol
X log p:2.412  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:4
Canonical Smiles:CC(CCC=C(C)C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Class:triterpene
Source:Euphorbia spp.
Reference:J Chem Soc 1944:249; 1958:179
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 52 active | as graph: single | with analogs [1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [52]
Species: 4932
Condition: YPT6
Replicates: 2
Raw OD Value: r im 0.2499±0.000989949
Normalized OD Score: sc h 0.8222±0.00888123
Z-Score: -4.9752±0.241083
p-Value: 0.000000907882
Z-Factor: 0.275511
Fitness Defect: 13.9122
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:4|B2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:25.80 Celcius
Date:2006-02-22 YYYY-MM-DD
Plate CH Control (+):0.04215000000000001±0.00092
Plate DMSO Control (-):0.324225±0.01237
Plate Z-Factor:0.8740
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DBLink | Rows returned: 277[1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [47]
90785 2-(3,8-dimethyl-1,2,3,3a,4,5,6,7-octahydroazulen-5-yl)propan-2-ol
92746 (3S,5S,10S,13S,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylhept-5-en-2-yl]-2,3,4,5,6,7,11,12,14,15,16,17-do
decahydro-1H-cyclopenta[a]phenanthren-3-ol
92762 2-[(2R,4aS,8aR)-4a,8-dimethyl-2,3,4,5,6,8a-hexahydro-1H-naphthalen-2-yl]propan-2-ol
101257 (3S,5S,10S,13S,14S,17S)-4,4,10,13,14-pentamethyl-17-[(2S)-6-methylhept-5-en-2-yl]-2,3,5,6,7,11,12,15,16,
17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
101770 (3S,5S,10S,13S,14R,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,11,12,14,15,16,17-dodec
ahydro-1H-cyclopenta[a]phenanthren-3-ol
102990 n/a

internal high similarity DBLink | Rows returned: 112 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 2
SPE00100583 0.253012048192771
SPE00240470 0

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