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Compound InformationSONAR Target prediction
Name:

EUPHOL

Unique Identifier:SPE00201697
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:376.32 g/mol
X log p:2.412  (online calculus)
Lipinksi Failures0
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:1
Rotatable Bond Count:4
Canonical Smiles:CC(CCC=C(C)C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC4(C)C=3CCC12C
Class:triterpene
Source:Euphorbia spp.
Reference:J Chem Soc 1944:249; 1958:179
Generic_name:LANOSTEROL
Chemical_iupac_name:LANOSTEROL
Drug_type:Experimental
Kegg_compound_id:C01724
Drugbank_id:EXPT02002
Logp:7.63
Cas_registry_number:79-63-0
Drug_category:Lanosterol Synthase inhibitor
Organisms_affected:-1

Found: 52 active | as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [52]
Species: 4932
Condition: BNI4
Replicates: 2
Raw OD Value: r im 0.7009±0.0623668
Normalized OD Score: sc h 1.1347±0.0345982
Z-Score: 4.1381±0.742416
p-Value: 0.000152821
Z-Factor: -1.15084
Fitness Defect: 8.7862
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:4|B2
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.70 Celcius
Date:2006-03-22 YYYY-MM-DD
Plate CH Control (+):0.039575±0.00047
Plate DMSO Control (-):0.6868±0.03393
Plate Z-Factor:0.8071
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DBLink | Rows returned: 277[1] << Back 21 22 23 24 25 26 27 28 29 30  Next >> [47]
5317337 n/a
5317423 (3S,10R,13S,17R)-17-(5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,5,6,9,11,12,14,15,16,17-dodecahydro-1
H-cyclopenta[a]phenanthren-3-ol
5317775 2,2,4a,6a,6b,9,9,12a-octamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-3,10-diol
5317959 n/a
5318052 2-[(6S)-6,10-dimethyl-2-spiro[4.5]dec-9-enyl]propan-2-ol
5318507 n/a

internal high similarity DBLink | Rows returned: 112 Next >> 
SPE01504073 0.9167
SPE01504051 0.9189
SPE01500847 0.9189
SPE00107022 0.9189
SPE00300055 0.9444
NRB 03722 0.9706

active | Cluster 1278 | Additional Members: 6 | Rows returned: 2
SPE00100583 0.253012048192771
SPE00240470 0

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