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Compound InformationSONAR Target prediction
Name:

FLAVOKAWAIN B

Unique Identifier:SPE00201610
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:
Molecular Weight:268.18 g/mol
X log p:19.808  (online calculus)
Lipinksi Failures1
TPSA35.53
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:5
Canonical Smiles:COc1cc(O)c(C(=O)C=Cc2ccccc2)c(OC)c1
Class:flavone
Source:Piper, Alpinia & Myrica spp
Reference:Z Naturforsch B 18: 370 (1963)

Found: 276 active | as graph: single | with analogs [1] << Back 261 262 263 264 265 266 267 268 269 270  Next >> [276]
Species: 4932
Condition: PFK2
Replicates: 2
Raw OD Value: r im 0.3891±0.0209304
Normalized OD Score: sc h 0.8055±0.0205976
Z-Score: -6.2490±0.72286
p-Value: 0.00000000480016
Z-Factor: 0.351666
Fitness Defect: 19.1546
Bioactivity Statement: Active
Experimental Conditions
Library:SPECMTS3
Plate Number and Position:11|B9
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.10 Celcius
Date:2008-05-10 YYYY-MM-DD
Plate CH Control (+):0.04045±0.00145
Plate DMSO Control (-):0.47715±0.01046
Plate Z-Factor:0.9186
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DBLink | Rows returned: 13<< Back 1 2 3 Next >> 
5708653 (E)-3-anthracen-9-yl-1-(2,4-dimethoxyphenyl)prop-2-en-1-one
5720587 (E)-1-(2,4-dimethoxyphenyl)-3-naphthalen-1-yl-prop-2-en-1-one
5837330 (E)-1-(2,4-dimethoxyphenyl)-3-phenyl-prop-2-en-1-one
6154317 (E)-3-phenyl-1-(2,4,6-trimethoxyphenyl)prop-2-en-1-one
6476742 (E)-1-(2,4-dimethoxyphenyl)-3-naphthalen-2-yl-prop-2-en-1-one
7946155 (E)-1-(2,4-dimethoxyphenyl)-3-(6-methoxynaphthalen-2-yl)prop-2-en-1-one

internal high similarity DBLink | Rows returned: 0

active | Cluster 9714 | Additional Members: 6 | Rows returned: 4
SPE01505153 0.551724137931034
SPE00201727 0.487179487179487
SPE00201081 0.458333333333333
SPE00200441 0

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