Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

GAMBOGIC ACID AMIDE

Unique Identifier:SPE00201522
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C38H45NO7
Molecular Weight:582.409 g/mol
X log p:10.586  (online calculus)
Lipinksi Failures1
TPSA78.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:8
Canonical Smiles:CC(C)=CCCC1(C)Oc2c(CC=C(C)C)c3OC45C6CC(C=C4C(=O)c3c(O)c2C=C1)C(=O)C5(C
C=C(C)C(N)=O)OC6(C)C
Source:derivative of Gambogic acid
Reference:Tetrahedron 21: 1453 (1965)

Found: 10 active | as graph: single | with analogs 1 2 3 4 5 6 7 8 9 10 Next >> 
Species: 4932
Condition: ARF1
Replicates: 2
Raw OD Value: r im 0.5753±0.0249609
Normalized OD Score: sc h 0.9129±0.0286192
Z-Score: -4.2188±1.37255
p-Value: 0.00058063
Z-Factor: -1.78934
Fitness Defect: 7.4514
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:7|E10
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.30 Celcius
Date:2007-10-02 YYYY-MM-DD
Plate CH Control (+):0.041425000000000003±0.00098
Plate DMSO Control (-):0.64175±0.02934
Plate Z-Factor:0.8538
png
ps
pdf

DBLink | Rows returned: 1
6710783

internal high similarity DBLink | Rows returned: 4
SPE00201524 0.9064
SPE10100009 0.9343
SPE00201539 0.9436
SPE00200007 0.9660

active | Cluster 84 | Additional Members: 8 | Rows returned: 6
SPE00201538 0.612403100775194
SPE00201540 0.410714285714286
SPE00201524 0.339449541284404
SPE00201539 0.333333333333333
SPE00210746 0.26605504587156
SPE00200007 0

Service provided by the Mike Tyers Laboratory