Compound Information | SONAR Target prediction | Name: | 7,8-DIHYDROXYFLAVONE | Unique Identifier: | SPE00201315 | MolClass: | Checkout models in ver1.5 and ver1.0 | Molecular Formula: | | Molecular Weight: | 244.158 g/mol | X log p: | 17.144 (online calculus) | Lipinksi Failures | 1 | TPSA | 26.3 | Hydrogen Bond Donor Count: | 0 | Hydrogen Bond Acceptors Count: | 4 | Rotatable Bond Count: | 1 | Canonical Smiles: | Oc1ccc2C(=O)C=C(Oc2c1O)c1ccccc1 | Class: | flavone | Source: | Godmania aesculifolia | Reference: | J Chem Soc 1939: 956, 958; 1956:4170 | Therapeutics: | vascular protectant, antihaemorrhagic |
Species: |
4932 |
Condition: |
MKK1 |
Replicates: |
2 |
Raw OD Value: r im |
0.8710±0.00141421 |
Normalized OD Score: sc h |
1.0608±0.00273499 |
Z-Score: |
1.7343±0.0182463 |
p-Value: |
0.0828892 |
Z-Factor: |
-0.993124 |
Fitness Defect: |
2.4903 |
Bioactivity Statement: |
Nonactive |
Experimental Conditions | | Library: | Spectrum_ED | Plate Number and Position: | 15|H6 | Drug Concentration: | 50.00 nM | OD Absorbance: | 595 nm | Robot Temperature: | 30.00 Celcius | Date: | 2010-08-10 YYYY-MM-DD | Plate CH Control (+): | 0.10275000000000001±0.01020 | Plate DMSO Control (-): | 0.981±0.03994 | Plate Z-Factor: | 0.8523 |
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DBLink | Rows returned: 1 | |
1880 |
7,8-dihydroxy-2-phenyl-chromen-4-one |
internal high similarity DBLink | Rows returned: 6 | |
active | Cluster 8175 | Additional Members: 1 | Rows returned: 0 | |
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