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Compound InformationSONAR Target prediction
Name:

7-HYDROXY-8,4`-DIMETHOXYISOFLAVONE

Unique Identifier:SPE00201185
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C17H14O5
Molecular Weight:284.179 g/mol
X log p:15.443  (online calculus)
Lipinksi Failures1
TPSA44.76
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:3
Canonical Smiles:COc1ccc(cc1)C1=COc2c(OC)c(O)ccc2C1=O
Source:semisynthetic analog

Found: 17 active | as graph: single | with analogs << Back 11 12 13 14 15 16 17
Species: 4932
Condition: VPS1
Replicates: 2
Raw OD Value: r im 0.5841±0.0151321
Normalized OD Score: sc h 0.8964±0.0270397
Z-Score: -4.1230±1.20457
p-Value: 0.000535676
Z-Factor: -4.0415
Fitness Defect: 7.532
Bioactivity Statement: Active
Experimental Conditions
Library:Spectrum
Plate Number and Position:5|A5
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:24.40 Celcius
Date:2007-10-03 YYYY-MM-DD
Plate CH Control (+):0.040075±0.00079
Plate DMSO Control (-):0.6422±0.06584
Plate Z-Factor:0.6188
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DBLink | Rows returned: 1
5319771 7-hydroxy-8-methoxy-3-(4-methoxyphenyl)chromen-4-one

internal high similarity DBLink | Rows returned: 4
SPE00240645 0.9407
SPE00201341 0.9571
SPE00200139 0.9710
SPE00201312 0.9926

nonactive | Cluster 5360 | Additional Members: 5 | Rows returned: 4
SPE00200139 0.440677966101695
SPE00201341 0.388888888888889
SPE00240645 0.288461538461538
SPE00201312 0

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