| Compound Information | SONAR Target prediction | | Name: | ANDROSTERONE ACETATE | | Unique Identifier: | SPE00107113 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | | | Molecular Weight: | 301.231 g/mol | | X log p: | -0.0390000000000001 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 43.37 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 3 | | Rotatable Bond Count: | 2 | | Canonical Smiles: | CC(=O)OC1CCC2(C)C(CCC3C2CCC2(C)C3CCC2=O)C1 | | Source: | semisynthetic | | Therapeutics: | androgen |
| Species: |
4932 |
| Condition: |
DEP1 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.5995±0.0292035 |
| Normalized OD Score: sc h |
0.8750±0.0454041 |
| Z-Score: |
-5.5004±1.48667 |
| p-Value: |
0.00000430974 |
| Z-Factor: |
-0.564734 |
| Fitness Defect: |
12.3546 |
| Bioactivity Statement: |
Active |
| Experimental Conditions | | | Library: | Spectrum | | Plate Number and Position: | 9|A8 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 25.40 Celcius | | Date: | 2005-12-22 YYYY-MM-DD | | Plate CH Control (+): | 0.039325±0.00366 | | Plate DMSO Control (-): | 0.68845±0.01406 | | Plate Z-Factor: | 0.9070 |
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ps
pdf |
| 7056381 |
2-[(3S,5S,8R,9S,10S,13S,14S,17S)-17-acetyloxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradeca
hydro-1H-cyclopenta[a]phenanthren-3-yl]acetate |
| 7056382 |
2-[(3S,5S,8R,9S,10S,13S,14S,17S)-17-acetyloxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradeca
hydro-1H-cyclopenta[a]phenanthren-3-yl]acetic acid |
| 7056383 |
2-[(3S,5S,8R,9S,10S,13S,14R,17S)-17-acetyloxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradeca
hydro-1H-cyclopenta[a]phenanthren-3-yl]acetate |
| 7056384 |
2-[(3S,5S,8R,9S,10S,13S,14R,17S)-17-acetyloxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradeca
hydro-1H-cyclopenta[a]phenanthren-3-yl]acetic acid |
| 7056466 |
[(3R,5S,8R,9R,10S,13S,14S)-3-ethyl-10,13-dimethyl-17-oxo-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyc
lopenta[a]phenanthren-3-yl] acetate |
| 7056467 |
[(3R,5S,8S,9R,10S,13S,14S)-3-ethyl-10,13-dimethyl-17-oxo-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyc
lopenta[a]phenanthren-3-yl] acetate |
| internal high similarity DBLink | Rows returned: 10 | 1 2 Next >> |
| active | Cluster 11774 | Additional Members: 14 | Rows returned: 5 | |
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