Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

5,7-dihydroxy-2,3-diphenyl-4H-chromen-4-one

Unique Identifier:RJC 00213
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C21H14O4
Molecular Weight:316.222 g/mol
X log p:25.033  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:2
Canonical Smiles:Oc1cc(O)c2C(=O)C(c3ccccc3)=C(Oc2c1)c1ccccc1

Found: 18 active as graph: single | with analogs << Back 1 2 3 4 5 6 7 8 9 10  Next >> 
Species: 4932
Condition: MKK1
Replicates: 2
Raw OD Value: r im 0.0985±0.0176777
Normalized OD Score: sc h 0.1583±0.0295473
Z-Score: -6.1459±0.604875
p-Value: 0.00000000540918
Z-Factor: 0.793695
Fitness Defect: 19.0352
Bioactivity Statement: Toxic
Experimental Conditions
Library:Cytotoxic
Plate Number and Position:7|C10
Drug Concentration:50.00 nM
OD Absorbance:595 nm
Robot Temperature:30.00 Celcius
Date:2010-08-10 YYYY-MM-DD
Plate CH Control (+):0.09425±0.00437
Plate DMSO Control (-):0.96925±0.02730
Plate Z-Factor:0.9131
png
ps
pdf

DBLink | Rows returned: 1
5904559 5,7-dihydroxy-2,3-diphenyl-chromen-4-one

internal high similarity DBLink | Rows returned: 1
RJC 00212 0.9769

active | Cluster 10732 | Additional Members: 22 | Rows returned: 72 Next >> 
SPE01505143 0.464285714285714
SPE01502259 0.421052631578947
Prest342 0.326923076923077
LOPAC 01061 0.326923076923077
Prest1133 0.224489795918367
Prest541 0

Service provided by the Mike Tyers Laboratory