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Compound InformationSONAR Target prediction
Name:

Antimycin A

Unique Identifier:Prest922
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C28H40N2O9
Molecular Weight:509.316 g/mol
X log p:6.022  (online calculus)
Lipinksi Failures3
TPSA113.04
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:11
Rotatable Bond Count:14
Canonical Smiles:CCCCCCC1C(OC(=O)CC(C)C)C(C)OC(=O)C(NC(=O)c2cccc(NC=O)c2O)C(C)OC1=O

Found: 3 nonactive as graph: single | with analogs 2 3 Next >> 
Species: 9606
Condition: TMPPre001
Replicates: 2
Raw OD Value: r im 1773.0000±0
Normalized OD Score: sc h 0.8518±0
Z-Score: -3.3407±0
p-Value: 0.000835576
Z-Factor: -13.4093
Fitness Defect: 7.0874
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Prestwick
Plate Number and Position:3|G3
Drug Concentration:50.00 nM
OD Absorbance:0 nm
Robot Temperature:23.60 Celcius
Date:2006-10-10 YYYY-MM-DD
Plate CH Control (+):1037.5±978.23463
Plate DMSO Control (-):2014±552.18250
Plate Z-Factor:-4.9321
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DBLink | Rows returned: 212 3 4 Next >> 
2204 [3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-8-pentyl-1,5-dioxonan-7-yl]
3-methylbutanoate
10652 [(6S,7S,8R)-8-butyl-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]
3-methylbutanoate
12550 [3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl]
3-methylbutanoate
14957 [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 3-methylbutanoate
245869 [(2R,3S,6S,7R,8R)-8-butyl-3-[(3-formamido-2-hydroxy-benzoyl)amino]-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 3-methylbutanoate
447434 [(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxy-benzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7
-yl] 2-methylpropanoate

internal high similarity DBLink | Rows returned: 0

active | Cluster 5241 | Additional Members: 4 | Rows returned: 1
SPE01502108 0

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