Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Practolol

Unique Identifier:Prest742
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C14H22N2O3
Molecular Weight:244.161 g/mol
X log p:7.795  (online calculus)
Lipinksi Failures1
TPSA26.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:5
Rotatable Bond Count:8
Canonical Smiles:CC(C)NCC(O)COc1ccc(NC(C)=O)cc1

Found: 3 nonactive as graph: single | with analogs 1 2 3 Next >> 
Species: 9606
Condition: TMPPre001
Replicates: 2
Raw OD Value: r im 2106.0000±0
Normalized OD Score: sc h 1.0055±0
Z-Score: 0.1235±0
p-Value: 0.90168
Z-Factor: -6.47682
Fitness Defect: 0.1035
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Prestwick
Plate Number and Position:5|B3
Drug Concentration:50.00 nM
OD Absorbance:0 nm
Robot Temperature:23.80 Celcius
Date:2006-10-10 YYYY-MM-DD
Plate CH Control (+):967.5±954.39230
Plate DMSO Control (-):2031±542.13094
Plate Z-Factor:-4.5046
png
ps
pdf

DBLink | Rows returned: 17<< Back 1 2 3 Next >> 
6918923 [(2R)-3-(4-acetamidophenoxy)-2-hydroxy-propyl]-propan-2-yl-azanium
6918924 N-[4-[(2R)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
6973633 [(2S)-3-(4-acetamidophenoxy)-2-hydroxy-propyl]-propan-2-yl-azanium
7166472 [(2S)-3-(4-acetamidophenoxy)-2-hydroxy-propyl]-diethyl-azanium
7166473 N-[4-[(2S)-3-diethylamino-2-hydroxy-propoxy]phenyl]acetamide
7166474 [(2R)-3-(4-acetamidophenoxy)-2-hydroxy-propyl]-diethyl-azanium

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 7246 | Additional Members: 18 | Rows returned: 141 2 3 Next >> 
LOPAC 00725 0.416666666666667
Prest779 0.416666666666667
SPE01505704 0.406779661016949
Prest1084 0.406779661016949
SPE01503632 0.358490566037736
Prest1009 0.333333333333333

Service provided by the Mike Tyers Laboratory