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Compound InformationSONAR Target prediction
Name:

Corticosterone

Unique Identifier:Prest672
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C21H30O4
Molecular Weight:319.246 g/mol
X log p:0.527  (online calculus)
Lipinksi Failures0
TPSA34.14
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:2
Canonical Smiles:CC12CC(O)C3C(CCC4=CC(=O)CCC34C)C1CCC2C(=O)CO

Found: 3 nonactive as graph: single | with analogs << Back 1 2 3 Next >> 
Species: 9606
Condition: TMPPre002
Replicates: 2
Raw OD Value: r im 10164.0000±0
Normalized OD Score: sc h 0.9588±0
Z-Score: -0.9288±0
p-Value: 0.353
Z-Factor: -18.023
Fitness Defect: 1.0413
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Prestwick
Plate Number and Position:6|D3
Drug Concentration:50.00 nM
OD Absorbance:0 nm
Robot Temperature:24.00 Celcius
Date:2006-10-10 YYYY-MM-DD
Plate CH Control (+):1009.5±953.84240
Plate DMSO Control (-):2021±558.06298
Plate Z-Factor:-4.4864
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DBLink | Rows returned: 112 Next >> 
5753 (8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17
-dodecahydrocyclopenta[a]phenanthren-3-one
165276 (8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-13-methyl-2,6,7,8,9,10,11,12,14,15,16,17-dod
ecahydro-1H-cyclopenta[a]phenanthren-3-one
256277 (8S,9S,10R,11R,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17
-dodecahydrocyclopenta[a]phenanthren-3-one
439739 11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phe
nanthren-3-one
439858 (8S,9S,10R,13R,14S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecah
ydrocyclopenta[a]phenanthren-3-one
534502 11-hydroxy-17-(2-hydroxyacetyl)-9,10,13-trimethyl-2,6,7,8,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]ph
enanthren-3-one

internal high similarity DBLink | Rows returned: 0

active | Cluster 10196 | Additional Members: 12 | Rows returned: 0

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