Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Palmatine chloride

Unique Identifier:Prest374
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C21ClH23NO4
Molecular Weight:365.682 g/mol
X log p:15.013  (online calculus)
Lipinksi Failures1
TPSA39.93
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:4
Canonical Smiles:[ClH-].COc1ccc2cc3c4cc(OC)c(OC)cc4CC[n+]3cc2c1OC

Found: 2 nonactive | as graph: single | with analogs 1 2 Next >> 
Species: 9606
Condition: TMPPre001
Replicates: 2
Raw OD Value: r im 1700.0000±0
Normalized OD Score: sc h 0.8515±0
Z-Score: -3.3473±0
p-Value: 0.000816
Z-Factor: -14.0944
Fitness Defect: 7.1111
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Prestwick
Plate Number and Position:8|B10
Drug Concentration:50.00 nM
OD Absorbance:0 nm
Robot Temperature:24.20 Celcius
Date:2006-10-10 YYYY-MM-DD
Plate CH Control (+):953±868.44324
Plate DMSO Control (-):1906.5±525.50956
Plate Z-Factor:-4.3660
png
ps
pdf

DBLink | Rows returned: 4
19009
73442
200119
3083876

internal high similarity DBLink | Rows returned: 0

active | Cluster 10382 | Additional Members: 9 | Rows returned: 4
Prest91 0
LAT002A08 0
LAT004G09 0
SPE01500811 0

Service provided by the Mike Tyers Laboratory