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Compound InformationSONAR Target prediction
Name:

Thiostrepton

Unique Identifier:Prest1117
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C72H85N19O18S5
Molecular Weight:1579.22 g/mol
X log p:9.515  (online calculus)
Lipinksi Failures3
TPSA427.09
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:37
Rotatable Bond Count:14
Canonical Smiles:CCC(C)C1NC2C=Cc3c(cc(nc3C2O)C(=O)OC(C)C2NC(=O)c3csc(n3)C(NC(=O)C3CSC(=
N3)C(NC(=O)C(NC(=O)c3csc(n3)C3(CCC(=NC3c3csc2n3)c2scc(n2)C(=O)NC(=C)C(
=O)NC(=C)C(N)=O)NC(=O)C(C)NC(=O)C(=C)NC(=O)C(C)NC1=O)C(C)O)=CC)C(C)(O)
C(C)O)C(C)O

Found: 3 nonactive as graph: single | with analogs << Back 1 2 3 Next >> 
Species: 9606
Condition: TMPPre002
Replicates: 2
Raw OD Value: r im 9642.0000±0
Normalized OD Score: sc h 0.9636±0
Z-Score: -0.8214±0
p-Value: 0.41144
Z-Factor: -10.3834
Fitness Defect: 0.8881
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Prestwick
Plate Number and Position:7|E3
Drug Concentration:50.00 nM
OD Absorbance:0 nm
Robot Temperature:24.10 Celcius
Date:2006-10-10 YYYY-MM-DD
Plate CH Control (+):951.5±923.27222
Plate DMSO Control (-):2006±543.99595
Plate Z-Factor:-4.4324
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DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 0

active | Cluster 1 | Additional Members: 50 | Rows returned: 141 2 3 Next >> 
LOPAC 00756 0
SPE01503428 0
LAT007G07 0
Prest1291 0
LAT007H07 0
LAT007E08 0

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