| Compound Information | SONAR Target prediction | | Name: | Cefepime hydrochloride | | Unique Identifier: | Prest1089 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C19ClH28N6O6S2 | | Molecular Weight: | 509.841 g/mol | | X log p: | 0.158 (online calculus) | | Lipinksi Failures | 0 | | TPSA | 139 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 8 | | Rotatable Bond Count: | 8 | | Canonical Smiles: | [ClH-].O.CON=C(C(=O)NC1C2SCC(C[N+]3(C)CCCC3)=C(N2C1=O)C(O)=O)c1csc(N)n
1 |
| Species: |
9606 |
| Condition: |
TMPPre003 |
| Replicates: |
2 |
| Raw OD Value: r im |
11244.0000±0 |
| Normalized OD Score: sc h |
0.9359±0 |
| Z-Score: |
-1.7845±0 |
| p-Value: |
0.0743338 |
| Z-Factor: |
-4.84645 |
| Fitness Defect: |
2.5992 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Prestwick | | Plate Number and Position: | 14|H9 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 0 nm | | Robot Temperature: | 23.60 Celcius | | Date: | 2006-10-10 YYYY-MM-DD | | Plate CH Control (+): | 22309.5±7874.12854 | | Plate DMSO Control (-): | 12130±7429.00076 | | Plate Z-Factor: | -6.0556 |
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ps
pdf |
| 5491295 |
(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(1-methyl-2,3,4,5-tetrahyd
ropyrrol-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| 5491422 |
(6R,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(1-methyl-2,3,4,5-tetrahyd
ropyrrol-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride dihydrate
hydrochloride |
| 6604586 |
(6S,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(1-methyl-2,3,4,5-tetrahyd
ropyrrol-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrate hydrochloride |
| 6604587 |
(6S,7R)-7-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(1-methyl-2,3,4,5-tetrahyd
ropyrrol-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| 6914286 |
(6S,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino]-3-[(1-methyl-2,3,4,5-tetrahyd
ropyrrol-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| internal high similarity DBLink | Rows returned: 0 | |
| active | Cluster 437 | Additional Members: 14 | Rows returned: 2 | |
|
