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Compound InformationSONAR Target prediction
Name:

Fluocinonide

Unique Identifier:Prest1066
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C26F2H32O7
Molecular Weight:464.287 g/mol
X log p:4.867  (online calculus)
Lipinksi Failures0
TPSA78.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:7
Rotatable Bond Count:4
Canonical Smiles:CC(=O)OCC(=O)C12OC(C)(C)OC1CC1C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C
Generic_name:Fluocinonide
Drug_type:Approved Drug
Pharmgkb_id:PA449664
Kegg_compound_id:D00325
Drugbank_id:APRD00978
Melting_point:309 oC
H2o_solubility:4.74 mg/L
Logp:2.734
Cas_registry_number:12/07/356
Drug_category:Anti-Allergic Agents; Anti-Inflammatory Agents; Glucocorticoids; ATC:C05AA11;
ATC:D07AC08
Indication:A topical anti-inflammatory product for the relief of the inflammatory and pruritic
manifestations of corticosteroid-responsive dermatoses.
Organisms_affected:Humans and other mammals

Found: 3 nonactive as graph: single | with analogs 2 3 Next >> 
Species: 9606
Condition: TMPPre001
Replicates: 2
Raw OD Value: r im 1178.0000±0
Normalized OD Score: sc h 0.9824±0
Z-Score: -0.3974±0
p-Value: 0.691082
Z-Factor: -43.8089
Fitness Defect: 0.3695
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Prestwick
Plate Number and Position:10|F5
Drug Concentration:50.00 nM
OD Absorbance:0 nm
Robot Temperature:23.30 Celcius
Date:2006-10-10 YYYY-MM-DD
Plate CH Control (+):870.5±769.75857
Plate DMSO Control (-):982.5±305.13061
Plate Z-Factor:-45.8313
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DBLink | Rows returned: 102 Next >> 
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9642
3083300
5702057
6604242
6710662

internal high similarity DBLink | Rows returned: 0

active | Cluster 2095 | Additional Members: 14 | Rows returned: 0

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