| Compound Information | SONAR Target prediction | | Name: | Camptothecine (S,+) | | Unique Identifier: | Prest102 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C20H16N2O4 | | Molecular Weight: | 332.225 g/mol | | X log p: | 11.182 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 58.97 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 6 | | Rotatable Bond Count: | 1 | | Canonical Smiles: | CCC1(O)C(=O)OCC2C(=O)N3Cc4cc5ccccc5nc4C3=CC=21 |
| Species: |
9606 |
| Condition: |
TMPPre003 |
| Replicates: |
2 |
| Raw OD Value: r im |
14605.0000±0 |
| Normalized OD Score: sc h |
0.7874±0 |
| Z-Score: |
-5.9143±0 |
| p-Value: |
0.00000000333224 |
| Z-Factor: |
-0.271146 |
| Fitness Defect: |
19.5196 |
| Bioactivity Statement: |
Active |
| Experimental Conditions | | | Library: | Prestwick | | Plate Number and Position: | 3|D11 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 0 nm | | Robot Temperature: | 23.60 Celcius | | Date: | 2006-10-10 YYYY-MM-DD | | Plate CH Control (+): | 18357.5±2177.01332 | | Plate DMSO Control (-): | 18529.5±1551.44299 | | Plate Z-Factor: | -61.5880 |
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| DBLink | Rows returned: 5 | |
| internal high similarity DBLink | Rows returned: 0 | |
| nonactive | Cluster 1530 | Additional Members: 9 | Rows returned: 6 | |
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