| Compound Information | SONAR Target prediction | | Name: | (±)-Thalidomide | | Unique Identifier: | LOPAC 01279 | | MolClass: | Checkout models in ver1.5 and ver1.0 | | Molecular Formula: | C13H10N2O4 | | Molecular Weight: | 248.15 g/mol | | X log p: | 6.737 (online calculus) | | Lipinksi Failures | 1 | | TPSA | 71.52 | | Hydrogen Bond Donor Count: | 0 | | Hydrogen Bond Acceptors Count: | 6 | | Rotatable Bond Count: | 1 | | Canonical Smiles: | O=C1CCC(n2c(=O)c3ccccc3c2=O)C(=O)N1 | | Class: | Cytoskeleton and ECM | | Action: | Inhibitor | | Selectivity: | TNFalpha |
| Species: |
4932 |
| Condition: |
WHI5 |
| Replicates: |
2 |
| Raw OD Value: r im |
0.6457±0.00282843 |
| Normalized OD Score: sc h |
1.0110±0.0149119 |
| Z-Score: |
0.3602±0.490914 |
| p-Value: |
0.734456 |
| Z-Factor: |
-4.31276 |
| Fitness Defect: |
0.3086 |
| Bioactivity Statement: |
Nonactive |
| Experimental Conditions | | | Library: | Lopac | | Plate Number and Position: | 16|C5 | | Drug Concentration: | 50.00 nM | | OD Absorbance: | 600 nm | | Robot Temperature: | 0.00 Celcius | | Date: | 2005-04-20 YYYY-MM-DD | | Plate CH Control (+): | 0.047475±0.00156 | | Plate DMSO Control (-): | 0.666825±0.09333 | | Plate Z-Factor: | 0.8067 |
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| DBLink | Rows returned: 0 | |
| internal high similarity DBLink | Rows returned: 0 | |
| active | Cluster 7702 | Additional Members: 4 | Rows returned: 0 | |
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