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Compound InformationSONAR Target prediction
Name:

Terbutaline hemisulfate

Unique Identifier:LOPAC 01240
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C24H40N2O10S
Molecular Weight:508.33 g/mol
X log p:5.569  (online calculus)
Lipinksi Failures1
TPSA0
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:4
Rotatable Bond Count:4
Canonical Smiles:CC(C)(C)NCC(O)c1cc(O)cc(O)c1.CC(C)(C)NCC(O)c1cc(O)cc(O)c1.OS(O)(=O)=O
Class:Adrenoceptor
Action:Agonist
Selectivity:beta

Found: 24 nonactive as graph: single | with analogs [1] << Back 21 22 23 24 Next >> [24]
Species: 4932
Condition: WHI3
Replicates: 2
Raw OD Value: r im 0.7628±0.121127
Normalized OD Score: sc h 0.9998±0.0216933
Z-Score: -0.1187±0.849085
p-Value: 0.551052
Z-Factor: -49.9824
Fitness Defect: 0.5959
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:15|A7
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-04-20 YYYY-MM-DD
Plate CH Control (+):0.04415±0.00828
Plate DMSO Control (-):0.70645±0.02743
Plate Z-Factor:0.8566
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DBLink | Rows returned: 4
31620 [2-(3,5-dihydroxyphenyl)-2-hydroxy-ethyl]-tert-butyl-azanium sulfate
441333 5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol; sulfuric acid
441334 5-[1-hydroxy-2-(tert-butylamino)ethyl]benzene-1,3-diol; sulfuric acid
657301 5-[1-hydroxy-2-(tert-butylamino)ethyl]benzene-1,3-diol; sulfuric acid

internal high similarity DBLink | Rows returned: 4
JFD 01582 0.9016
SPE01500390 0.9032
LOPAC 01034 1.0000
SPE01500558 1.0000

active | Cluster 17428 | Additional Members: 9 | Rows returned: 0

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