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Compound InformationSONAR Target prediction
Name:

Phorbol 12-myristate 13-acetate

Unique Identifier:LOPAC 01158
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C36H56O8
Molecular Weight:563.404 g/mol
X log p:1.237  (online calculus)
Lipinksi Failures1
TPSA69.67
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:8
Rotatable Bond Count:17
Canonical Smiles:CCCCCCCCCCCCCC(=O)OC1C(C)C2(O)C(C=C(CO)CC3(O)C2C=C(C)C3=O)C2C(C)(C)C12
OC(C)=O
Class:Phosphorylation
Action:Activator
Selectivity:PKC

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: KRE1
Replicates: 2
Raw OD Value: r im 0.6605±0.00671751
Normalized OD Score: sc h 1.0028±0.00809484
Z-Score: 0.1270±0.350154
p-Value: 0.805986
Z-Factor: -7.57646
Fitness Defect: 0.2157
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:13|H3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:27.90 Celcius
Date:2005-11-22 YYYY-MM-DD
Plate CH Control (+):0.03925±0.00175
Plate DMSO Control (-):0.634375±0.02407
Plate Z-Factor:0.8702
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DBLink | Rows returned: 401 2 3 4 5 6 7 Next >> 
4792
27924
37783
122634
124027
124127

internal high similarity DBLink | Rows returned: 1
SPE00330004 1.0000

active | Cluster 717 | Additional Members: 7 | Rows returned: 0
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