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Compound InformationSONAR Target prediction
Name:

Propionylpromazine hydrochloride

Unique Identifier:LOPAC 01155
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C20ClH25N2OS
Molecular Weight:351.746 g/mol
X log p:15.516  (online calculus)
Lipinksi Failures1
TPSA48.85
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:3
Rotatable Bond Count:6
Canonical Smiles:Cl.CCC(=O)c1ccc2Sc3ccccc3N(CCCN(C)C)c2c1
Class:Dopamine
Action:Antagonist
Selectivity:DRD2

Found: 24 nonactive as graph: single | with analogs [1] << Back 11 12 13 14 15 16 17 18 19 20  Next >> [24]
Species: 4932
Condition: SAP30
Replicates: 2
Raw OD Value: r im 0.8011±0.000212132
Normalized OD Score: sc h 1.0049±0.00390033
Z-Score: 0.4117±0.309582
p-Value: 0.687684
Z-Factor: -18.0212
Fitness Defect: 0.3744
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:13|D3
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.20 Celcius
Date:2005-11-18 YYYY-MM-DD
Plate CH Control (+):0.039150000000000004±0.00126
Plate DMSO Control (-):0.7788250000000001±0.01996
Plate Z-Factor:0.9342
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DBLink | Rows returned: 3
24351 1-[10-(3-dimethylaminopropyl)phenothiazin-2-yl]propan-1-one hydrochloride
24352 1-[10-(3-dimethylaminopropyl)phenothiazin-2-yl]propan-1-one
6921790 dimethyl-[3-(2-propanoylphenothiazin-10-yl)propyl]azanium

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 17541 | Additional Members: 13 | Rows returned: 121 2 Next >> 
SPE01505498 0.35
Prest888 0.35
Prest536 0.32258064516129
LOPAC 01145 0.32258064516129
SPE01503934 0.32258064516129
LOPAC 01148 0.3

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