Home | Screening data | Screen comparisons | Search for compounds | Structure search

Compound InformationSONAR Target prediction
Name:

Piroxicam

Unique Identifier:LOPAC 01144
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C15H13N3O4S
Molecular Weight:318.244 g/mol
X log p:16.369  (online calculus)
Lipinksi Failures1
TPSA75.19
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:7
Rotatable Bond Count:3
Canonical Smiles:CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O
Class:Prostaglandin
Action:Inhibitor
Selectivity:COX

Found: 24 nonactive as graph: single | with analogs [1] << Back 1 2 3 4 5 6 7 8 9 10  Next >> [24]
Species: 4932
Condition: BY4743
Replicates: 2
Raw OD Value: r im 0.6828±0.0500632
Normalized OD Score: sc h 0.9421±0.0508879
Z-Score: -1.5562±1.32295
p-Value: 0.273756
Z-Factor: -4.0731
Fitness Defect: 1.2955
Bioactivity Statement: Nonactive
Experimental Conditions
Library:Lopac
Plate Number and Position:12|B11
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:0.00 Celcius
Date:2005-08-19 YYYY-MM-DD
Plate CH Control (+):0.0514±0.00217
Plate DMSO Control (-):0.6902250000000001±0.03299
Plate Z-Factor:0.9048
png
ps
pdf

DBLink | Rows returned: 0

internal high similarity DBLink | Rows returned: 1
SPE01500491 1.0000

active | Cluster 16469 | Additional Members: 9 | Rows returned: 5
SPE01504150 0.353846153846154
Prest505 0.295081967213115
SPE01503242 0.295081967213115
Prest573 0
SPE01500491 0

Service provided by the Mike Tyers Laboratory