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Compound InformationSONAR Target prediction
Name:

Mitoxantrone

Unique Identifier:LOPAC 01057
MolClass: Checkout models in ver1.5 and ver1.0
Molecular Formula:C22Cl2H30N4O6
Molecular Weight:487.164 g/mol
X log p:6.694  (online calculus)
Lipinksi Failures2
TPSA34.14
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptors Count:10
Rotatable Bond Count:12
Canonical Smiles:Cl.Cl.OCCNCCNc1ccc(NCCNCCO)c2c(=O)c3c(O)ccc(O)c3c(=O)c12
Class:DNA Metabolism
Action:Inhibitor

Found: 5 active | as graph: single | with analogs 2 3 4 5 Next >> 
Species: 4932
Condition: DEP1
Replicates: 2
Raw OD Value: r im 0.5340±0.00487904
Normalized OD Score: sc h 0.9003±0.0170998
Z-Score: -4.0783±0.518149
p-Value: 0.000107244
Z-Factor: 0.0589499
Fitness Defect: 9.1404
Bioactivity Statement: Active
Experimental Conditions
Library:Lopac
Plate Number and Position:10|F10
Drug Concentration:50.00 nM
OD Absorbance:600 nm
Robot Temperature:26.90 Celcius
Date:2005-11-16 YYYY-MM-DD
Plate CH Control (+):0.0392±0.00130
Plate DMSO Control (-):0.590575±0.00799
Plate Z-Factor:0.9457
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DBLink | Rows returned: 1
4212 5,8-dihydroxy-1,4-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione

internal high similarity DBLink | Rows returned: 0

nonactive | Cluster 14085 | Additional Members: 3 | Rows returned: 1
SPE01503278 0

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